October 14, 2017
by Artem Kaznatcheev
This is the 250th post on the Theory, Evolutionary, and Games Group Blog. And although my posting pace has slowed in recent months, I see this as a milestone along the continuing road of open science. And I want to take this post as an opportunity to make some comments on open science.
To get this far, I’ve relied on a lot of help and encouragement. Both directly from all the wonderful guest posts and comments, and indirectly from general recognition. Most recently, this has taken the form of the Canadian blogging and science outreach network Science Borealis recognized us as one of the top 12 science blogs in Canada.
Given this connection, it is natural to also view me as an ally of other movements associated with open science; like, (1) preprints and (2) post-publication peer-review (PPPR). To some extent, I do support both of these activities. First, I regularly post my papers to ArXiv & BioRxiv. Just in the two preceeding months, I’ve put out a paper on the complexity of evolutionary equilibria and joint work on how fibroblasts and alectinib switch the games that cancers play. Another will follow later this month based on our project during the 2016 IMO Workshop. And I’ve been doing this for a while: the first draft of my evolutionary equilibria paper, for example, is older than BioRxiv — which only launched in November 2013. More than 20 years after physicists, mathematicians, and computer scientists started using ArXiv.
Second, some might think of my blog posts as PPPRs. For example. occasionally I try to write detailed comments on preprints and published papers. For example, my post on fusion and sex in proto-cells commenting on a preprint by Sam Sinai, Jason Olejarz and their colleagues. Finally, I am impressed and made happy by the now iconic graphic on the growth of preprints in biology.

But that doesn’t mean I find these ideas to be beyond criticism, and — more importantly — it doesn’t mean that there aren’t poor reasons for supporting preprints and PPPR.
Recently, I’ve seen a number of articles and tweets written on this topic both for and against (or neutral toward) pre-prints and for PPPR. Even Nature is telling us to embrace preprints. In the coming series of posts, I want to share some of my reflections on the case for preprints, and also argue that there isn’t anything all that revolutionary or transformative in them. If we want progress then we should instead think in terms of working papers. And as for post-publications peer review — instead, we should promote a culture of commentaries, glosses, and literature review/synthesis.
Currently, we do not publish papers to share ideas. We have ideas just to publish papers. And we need to change this aspect academic culture.
In this post, I will sketch some of the problems with academic publishing. Problems that I think any model of sharing results will have to address.
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Blogging community of computational and mathematical oncologists
July 27, 2019 by Artem Kaznatcheev 2 Comments
A few weeks ago, David Basanta reached out to me (and many other members of the mathematical oncology community) about building a community blog together. This week, to coincide with the Society for Mathematical Biology meeting in Montreal, we launched the blog. In keeping with the community focus, we have an editorial board of 8 people that includes (in addition to David and me): Christina Curtis, Elana Fertig, Stacey Finley, Jakob Nikolas Kather, Jacob G. Scott, and Jeffrey West. The theme is computational and mathematical oncology, but we welcome contributions from all nearby disciplines.
The behind the scenes discussion building up to this launch was one of the motivators for my post on twitter vs blogs and science advertising versus discussion. And as you might expect, dear reader, it was important to me that this new community blog wouldn’t be just about science outreach and advertising of completed work. For me — and I think many of the editors — it is important that the blog is a place for science engagement and for developing new ideas in the open. A way to peel back the covers that hide how science is done and break the silos that inhibit a collaborative and cooperative atmosphere. A way to not only speak at the public or other scientists, but also an opportunity to listen.
For me, the blog is a challenge to the community. A challenge to engage in more flexible, interactive, and inclusive development of new ideas than is possible with traditional journals. While also allowing for a deeper, more long-form and structured discussion than is possible with twitter. If you’ve ever written a detailed research email, long discussion on Slack, or been part of an exciting journal club, lab meeting, or seminar, you know the amount of useful discussion that is foundational to science but that seldom appears in public. My hope is that we can make these discussions more public and more beneficial to the whole community.
Before pushing for the project, David made sure that he knew the lay of the land. He assembled a list of the existing blogs on computational and mathematical oncology. In our welcome post, I made sure to highlight a few of the examples of our community members developing new ideas, sharing tools and techniques, and pushing beyond outreach and advertising. But since we wanted the welcome post to be short, there was not the opportunity for a more thorough survey of our community.
In this post, I want to provide a more detailed — although never complete nor exhaustive — snapshot of the blogging community of computational and mathematical oncologists. At least the part of it that I am familiar with. If I missed you then please let me know. This is exactly what the comments on this post are for: expanding our community.
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